Which stage of ROP is characterized by moderately abnormal blood vessel growth?

Stage 2 ROP is characterized by moderately abnormal blood vessel growth. In this stage, the blood vessels in the retina are more disorganized than in Stage 1, where they are simply present but not yet exhibiting significant abnormalities. In Stage 2, you see more pronounced changes, indicating that the growth of the blood vessels is not only poorly coordinated but may also begin to disrupt the normal vascular architecture of the retina. This can lead to complications if not monitored and managed appropriately.

Stage 1 ROP typically has normal blood vessel development, exhibiting a slightly abnormal border between the vascularized and non-vascularized retina but does not show the more significant disorganization seen in Stage 2. In Stage 3, the abnormal blood vessel growth becomes more severe and may develop into new vessels that proliferate, leading to further complications. Stage 4 ROP indicates retinal detachment due to neovascularization and scarring, showcasing even more advanced pathology compared to Stage 2. Thus, Stage 2 serves as a critical midpoint where intervention may be necessary to prevent progression to more severe stages.