What are the main symptoms of CHARGE syndrome?

CHARGE syndrome is a complex genetic condition characterized by a range of symptoms that can affect multiple systems in the body. The acronym CHARGE represents the major features associated with this syndrome: Coloboma (a defect in one or more of the eye structures), Heart defects, Atresia of the choanae (blockage of the nasal passages), Retardation of growth and development, Genital abnormalities, and Ear abnormalities including hearing loss.

The correct answer highlights that the symptoms associated with CHARGE syndrome encompass a wide variety of issues, including hearing loss and vision loss, heart defects, renal issues, coloboma, and growth retardation. Each of these features reflects the multifaceted nature of the syndrome, where individuals may present with a combination of symptoms from the different categories. This complexity necessitates a comprehensive understanding of the syndrome for effective diagnosis and management.

Understanding the diverse manifestations of CHARGE syndrome is crucial for healthcare professionals in providing appropriate care and support for affected individuals and their families. Recognizing that all listed symptoms are pertinent to CHARGE syndrome reinforces the need to monitor and address each aspect of the condition in clinical settings.